Chlorpyrifos is a broad spectrum organophosphate insecticide used for effective control of a wide range of soil and foliar pests in agricultural and non‑crop settings. It works by inhibiting acetylcholinesterase in insects, leading to rapid knockdown and prolonged residual activity. Formulations include emulsifiable concentrates, wettable powders, granules, and seed treatments, offering flexibility for application as foliar sprays, soil incorporation, or in‑furrow treatments. Chlorpyrifos is effective against aphids, cutworms, rootworms, borers, termites, and many other chewing and sucking pests. It is commonly used in crops such as corn, soybeans, cotton, rice, vegetables, fruits, and turf. Due to its toxicity profile, chlorpyrifos is a restricted use product in many regions and must be handled only by certified applicators following strict safety protocols, including proper personal protective equipment and adherence to label restrictions. Users should comply with all local regulations regarding application timing, buffer zones, and crop rotation intervals. For professional pest management, chlorpyrifos remains a powerful tool when used responsibly.

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